Also named as "Reishi", famous for its popular application with Cancer patients.
Ganoderma lucidum (a.k.a. lingzhi mushroom) is one of the oldest mushrooms known to be used medicinally.
Biologically active components of G. lucidum have been demonstrated to possess anti-tumor properties, anti-inflammatory, antihepatoxic, as well as anti-viral (e.g. herpes, influenza virus, Vesicular stomatitis) and anti-bacterial (e.g. Aspergillus niger, Bacillus cereus, E-coli) effects.
By targeting different stages of cancer development, G. lucidum suppresses the growth and migration of prostate cancer cells, ovarian cancer cells, Heps tumor, and colon cancer.
In addition, one oncologic study published in 2011 showed that G. lucidum can enhance the sensitivity of epithelial ovarian cancer cells to chemotherapy drug, cisplatin (Zhao, et al.). G. lucidum has also been reported to have immunomodulatory activities. Polysaccharides extracted from Ganoderma lucidum exerts antagonistic effects on the immunosuppression induced by melanoma cells on lymphochtes. Such finding suggests lingzhi mushroom’s potential in cancer immunotherapy (Sun et al.). Furthermore, investigations on the anti-oxidative and anti-inflammatory properties of G. lucidum consider G. lucidum as a promising agent for the prevention and treatments of Alzheimers disease (Zhou et al.) and Parkinson’s disease (Ding et al.).
Other laboratory studies indicate that lingzhi has therapeutic value in lowering cholesterol, blood pressure, and blood sugar.